Friday, October 23, 2015

Phthalimide Conjugation: The “Black Spot” for Targeted Protein Destruction


via Accelerating Science » Amanda Maxwell http://ift.tt/1PKXfwR

“And now, shipmates, this black spot? ‘Tain’t much good now, is it?”   ― Robert Louis Stevenson, Treasure Island   Imagine being able to specifically target a cancer protein for immediate destruction, slipping Robert Louis Stevenson’s notorious black spot into a crevice in the secondary structure and spelling imminent death. Well, this is what Winter et Read the rest of this article

The post Phthalimide Conjugation: The “Black Spot” for Targeted Protein Destruction appeared first on Accelerating Science.



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